ANTIPHLOGISTIC AGENT, AND REMEDY OF INFLAMMATORY DISEASE IN ARTHRITIS

Title:

ANTIPHLOGISTIC AGENT, AND REMEDY OF INFLAMMATORY DISEASE IN ARTHRITIS

Document Type and Number:

Japanese Patent JP2009023935

Kind Code:

A

Abstract:

To provide an antiphlogistic agent and a remedy of inflammatory disease in arthritis which has little side effects, high safety, and therapeutic effects.

The antiphlogistic agent and the remedy of the inflammatory disease in the arthritis comprise mangiferin as an active ingredient. The antiphlogistic agent having no side effect, high safety and excellent antiphlogistic effects can be provided. Also, the remedy of the inflammatory disease in the arthritis for ameliorating the inflammatory disease such as the arthritis is provided.

Inventors:

MATSUDA HIDEAKI
NISHIDA SHOZO

Application Number:

JP2007187837A

Publication Date:

February 05, 2009

Filing Date:

July 19, 2007

Export Citation:

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Assignee:

UNIV KINKI

International Classes:

A61K31/7048; A61P19/02; A61P29/00; C07H17/04

Other References:

JPN6012052131; ＳＡＲＫＡＲ，Ａ．　ｅｔ　ａｌ: 'ｂｅｔａ-Ｄ-Ｇｌｕｃｏｓｉｄｅ　ｓｕｐｐｒｅｓｓｅｓ　ｔｕｍｏｒ　ｎｅｃｒｏｓｉｓ　ｆａｃｔｏｒ-ｉｎｄｕｃｅｄ　ａｃｔｉｖａｔｉｏｎ　ｏｆ　ｎｕｃｌｅａｒ　ｔｒａｎｓｃｒｉｐｔｉｏｎ　ｆａｃｔｏｒ' Ｊ　Ｂｉｏｌ　ＣｈｅｍＶｏｌ．２７９，　Ｎｏ．３２, 2004, ｐ．３３７６８-８１
JPN6012052132; ＧＡＲＣＩＡ，Ｄ．　ｅｔ　ａｌ: 'Ｍｏｄｕｌａｔｉｏｎ　ｏｆ　ｒａｔ　ｍａｃｒｏｐｈａｇｅ　ｆｕｎｃｔｉｏｎ　ｂｙ　ｔｈｅ　Ｍａｎｇｉｆｅｒａ　ｉｎｄｉｃａ　Ｌ．　ｅｘｔｒａｃｔｓ　Ｖｉｍａｎｇ　ａｎｄ　ｍａｎｇｉｆｅｒｉｎ' Ｉｎｔ　ＩｍｍｕｎｏｐｈａｒｍａｃｏｌＶｏｌ．２，　Ｎｏ．６, 2002, ｐ．７９７-８０６
JPN6012052133; ＧＡＲＲＩＤＯ，Ｇ．　ｅｔ　ａｌ: 'Ｉｎ　ｖｉｖｏ　ａｎｄ　ｉｎ　ｖｉｔｒｏ　ａｎｔｉ-ｉｎｆｌａｍｍａｔｏｒｙ　ａｃｔｉｖｉｔｙ　ｏｆ　Ｍａｎｇｉｆｅｒａ　ｉｎｄｉｃａ　Ｌ．　ｅｘｔｒａｃｔ　（ＶＩＭＡＮＧ）' Ｐｈａｒｍａｃｏｌ　ＲｅｓＶｏｌ．５０，　Ｎｏ．２, 2004, ｐ．１４３-９
JPN6012052135; ＬＩＮ，Ｎ．　ｅｔ　ａｌ: 'Ｔｒｉｐｔｏｌｉｄｅ，　ａ　ｄｉｔｅｒｐｅｎｏｉｄ　ｔｒｉｅｐｏｘｉｄｅ，　ｓｕｐｐｒｅｓｓｅｓ　ｉｎｆｌａｍｍａｔｉｏｎ　ａｎｄ　ｃａｒｔｉｌａｇｅ　ｄｅｓｔｒｕｃｔｉｏｎ　ｉｎ　ｃｏｌｌａｇｅｎ-' Ｂｉｏｃｈｅｍ　ＰｈａｒｍａｃｏｌＶｏｌ．７３，　Ｎｏ．１, 2007, ｐ．１３６-４６

Attorney, Agent or Firm:

Tsuyoshi Takahashi
Masakazu Takahashi
Tomokazu Takahashi

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