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Title:
ANTIPHLOGISTIC AGENT, AND REMEDY OF INFLAMMATORY DISEASE IN ARTHRITIS
Document Type and Number:
Japanese Patent JP2009023935
Kind Code:
A
Abstract:

To provide an antiphlogistic agent and a remedy of inflammatory disease in arthritis which has little side effects, high safety, and therapeutic effects.

The antiphlogistic agent and the remedy of the inflammatory disease in the arthritis comprise mangiferin as an active ingredient. The antiphlogistic agent having no side effect, high safety and excellent antiphlogistic effects can be provided. Also, the remedy of the inflammatory disease in the arthritis for ameliorating the inflammatory disease such as the arthritis is provided.


Inventors:
MATSUDA HIDEAKI
NISHIDA SHOZO
Application Number:
JP2007000187837
Publication Date:
February 05, 2009
Filing Date:
July 19, 2007
Export Citation:
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Assignee:
UNIV KINKI
International Classes:
A61K31/7048; A61P19/02; A61P29/00; C07H17/04
Foreign References:
Other References:
JPN6012052131; SARKAR,A. et al: 'beta-D-Glucoside suppresses tumor necrosis factor-induced activation of nuclear transcription factor' J Biol Chem Vol.279, No.32, 2004, p.33768-81
JPN6012052132; GARCIA,D. et al: 'Modulation of rat macrophage function by the Mangifera indica L. extracts Vimang and mangiferin' Int Immunopharmacol Vol.2, No.6, 2002, p.797-806
JPN6012052133; GARRIDO,G. et al: 'In vivo and in vitro anti-inflammatory activity of Mangifera indica L. extract (VIMANG)' Pharmacol Res Vol.50, No.2, 2004, p.143-9
JPN6012052135; LIN,N. et al: 'Triptolide, a diterpenoid triepoxide, suppresses inflammation and cartilage destruction in collagen-' Biochem Pharmacol Vol.73, No.1, 2007, p.136-46
Attorney, Agent or Firm:
高橋 剛
高橋 雅和
高橋 友和