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Title:
C5-SUBSTITUTED PYRIMIDINE OR N6-SUBSTITUTED PURINE-2'-DEOXYNUCLEOTIDE DERIVATIVE AND METHOD FOR SYNTHESIZING NUCLEIC ACID USING THE SAME
Document Type and Number:
Japanese Patent JP2005060240
Kind Code:
A
Abstract:

To provide a C5-substituted deoxycytidine derivative or an N6-substituted deoxyadenosine derivative enzymically synthesizing modified DNAs especially required for DNA analysis with a DNA chip and to provide a method for synthesizing nucleic acid using the same.

The C5-substitured deoxycytidine derivative is characterized in that the derivative is represented by general formula {wherein, R denotes an NHX; and X denotes a hydrogen atom, an alkynyl group, an alkenyl group, an alkynyl group or an aryl group, a COCF3 group, a COCH3 group, a carbonylmethylimidazole group, a CH(=NH)NH2, a biotinyl group, various amino acids bound through amide bonds or a (CH2)2N[(CH2)2NH2]2 group}.


Inventors:
SAWAI HIROAKI
KUWABARA MASAYASU
Application Number:
JP2003207194A
Publication Date:
March 10, 2005
Filing Date:
August 11, 2003
Export Citation:
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Assignee:
UNIV GUNMA
International Classes:
C12P19/34; C07H19/10; C07H19/20; (IPC1-7): C07H19/10; C07H19/20; C12P19/34