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Title:
CAYAE 1
Document Type and Number:
Japanese Patent JPH10201490
Kind Code:
A
Abstract:

To obtain a polypeptide caYAE 1 having an amino acid sequence homology to the essential protein YAE 1 (scYAE 1) of Saccharomyces cerevisiae and useful for inducing immunological responses to fungi, especially Candida or Aspergillus.

This polypeptide caYAE 1 has an amino acid sequence of the formula and is originated from the gene of Candida albicans. The polypeptide caYAE 1 is contained by cloning a chromosomal DNA from Candida albicans B792, determining the sequence of the cloned chromosomal DNA fragment, isolating a perfectly long YAE 1 homology from the genoma library of the Candida albicans having plasmid YEp 13 and subsequently subjecting the obtained polynucleotide to a DNA recombination technology.


Inventors:
FREEMAN KATHRYN BELINDA
NICHOLAS RICHARD OAKLY
LIVI GEORGE PIETRO
Application Number:
JP36242797A
Publication Date:
August 04, 1998
Filing Date:
November 21, 1997
Export Citation:
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Assignee:
SMITHKLINE BEECHAM CORP
International Classes:
G01N33/53; A61K38/00; A61K39/395; A61K45/00; A61K48/00; A61P31/04; C07K14/395; C07K14/40; C07K16/14; C12N5/10; C12N15/09; C12N15/31; C12Q1/68; (IPC1-7): C12N15/09; A61K38/00; A61K39/395; A61K45/00; A61K48/00; C07K14/395; C07K14/40; C07K16/14; C12N5/10; C12Q1/68; G01N33/53
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)



 
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