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Title:
COMPOSITION FOR INHIBITING OSTEOCLAST DIFFERENTIATION
Document Type and Number:
Japanese Patent JP2012102021
Kind Code:
A
Abstract:

To provide a composition for inhibiting differentiation that inhibits differentiation of osteoclast precursor cells to osteoclasts and comprises D-allose as an active ingredient.

The composition for inhibiting differentiation to osteoclast inhibits differentiation of osteoclast precursor cells to osteoclasts by promoting expression of thioredoxin-interacting protein (TXNIP) or inhibiting expression of thioredoxin and contains D-allose as an active ingredient.


Inventors:
TOKUDA MASAAKI
YAMAGUCHI AYANORI
NOGUCHI CHISATO
YAMADA KANA
Application Number:
JP2010249075A
Publication Date:
May 31, 2012
Filing Date:
November 05, 2010
Export Citation:
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Assignee:
UNIV KAGAWA
KISHOTO SEISAN GIJUTSU KENKYUSHO KK
MATSUTANI KAGAKU KOGYO KK
International Classes:
A61K31/7004; A23L1/30; A61P19/00; A61P19/02; A61P19/10; A61P43/00; C07H3/02
Domestic Patent References:
JP2003128556A2003-05-08
Foreign References:
WO2003097820A12003-11-27
Attorney, Agent or Firm:
Asako Sudo
Akinobu Sudo