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Title:
COMPOSITIONS AND PRODUCTS CONTAINING ENANTIOMERIC EQUOL, AND PRODUCTION METHODS THEREOF
Document Type and Number:
Japanese Patent JP2016053027
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide a composition for use in the production of commercial foods and skin products, the composition consisting of S-equol, R-equol, or a mixture comprising a non-racemate and racemate of S-equol and R-equol.SOLUTION: The composition can be used for producing commercial products, such as food supplements, pharmaceuticals, and pharmaceutical compositions. The composition is useful for methods of administering S-equol to the mammals in order to prevent or treat diseases or related conditions comprising cardiovascular disease, lipid disorder, osteopenia, osteoporosis, liver disease, and hormone-dependent diseases, such as acute lack of ovarian estrogen. The S-equol enantiomer can be produced from isoflavone metabolism by biosynthesis with microorganisms.SELECTED DRAWING: Figure 1

Inventors:
SETCHELL KENNETH DAVID REGINALD
COLE SIDNEY JOHN
Application Number:
JP2015182750A
Publication Date:
April 14, 2016
Filing Date:
September 16, 2015
Export Citation:
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Assignee:
CHILDRENS HOSPITAL MED CT
AUSTRALIAN HEALTH & NUTRITION ASS LTD
International Classes:
A61K31/353; A01N37/00; A01N37/30; A23L33/00; A23L33/10; A61K31/7048; A61K47/00; A61P1/00; A61P1/04; A61P1/16; A61P3/06; A61P5/30; A61P9/00; A61P11/00; A61P13/08; A61P17/00; A61P19/08; A61P19/10; A61P25/28; A61P35/00; C07D311/74; A61K
Foreign References:
WO1999007392A11999-02-18
WO2000049009A12000-08-24
Other References:
JPN6015009054; 金城順英: '植物性エストロゲン' 日本臨床 第58巻第12号, 20001201, 第60〜64頁
JPN6015009056; E.Alvira et al: 'Molecular modelling study for chiral separation of equol enantiomers by beta-cyclodextrin' Chemical Physics Vol.240, 1999, p101-108
JPN6015051230; Ian R.Rowland et al: Nutrition and Cancer Vol.36 No.1, 2000, p27-32
JPN6015051228; M S Morton et al: Journal of Endocrinology Vol.142, 1994, p251-259
JPN6015051232; Herman Adlercreutz et al: The Lancet Vol.342, 1993, p1209-1210
Attorney, Agent or Firm:
深見 久郎
森田 俊雄
堀井 豊
野田 久登