Title:
CYCLIC AMINOPYRAZOLE AMIDE DERIVATIVE
Document Type and Number:
Japanese Patent JP2010180177
Kind Code:
A
Abstract:
To provide a 11βHSD1 inhibitor useful as a medicine for preventing and/or treating diseases such as diabetes.
There is provided a compound represented by formula (1) or a pharmaceutically acceptable salt thereof. Therein, RA is alkyl or the like; RB is a halogen atom or the like; RC is OH or the like; RD is a group represented by formula (2); ring A is a ring comprising 2 to 7C and N; RQ is alkyl or the like; (n) is 0 to 3; Rw is a single bond or the like; Rx is -NR1CO-, or the like; Ry is a single bond or the like; Rz is aryl or the like; R1 is H or the like.
Inventors:
HORIUCHI YOSHIHIRO
NUMANAMI TOMOFURU
TATAMIYA YOSHIHITO
SUDA HITOSHI
UNO SHINSAKU
NUMANAMI TOMOFURU
TATAMIYA YOSHIHITO
SUDA HITOSHI
UNO SHINSAKU
Application Number:
JP2009026663A
Publication Date:
August 19, 2010
Filing Date:
February 06, 2009
Export Citation:
Assignee:
DAINIPPON SUMITOMO PHARMA CO
International Classes:
C07D401/04; A61K31/4155; A61K31/4439; A61K31/454; A61K31/4545; A61P3/04; A61P3/06; A61P3/10; A61P9/00; A61P9/08; A61P9/10; A61P9/12; A61P19/10; A61P25/00; A61P25/24; A61P25/28; A61P27/02; A61P27/06; A61P37/02; A61P43/00; C07D401/14; C07D403/04; C07D409/14; C07D413/14; C07D417/14
Attorney, Agent or Firm:
Yobe
Mayumi Matsuo
Horikawa Tamaki
Yuki Ito
Mayumi Matsuo
Horikawa Tamaki
Yuki Ito