Title:
D-キシロピラノシル置換フェニル、前記化合物を含む薬物、その使用、及びその製造方法
Document Type and Number:
Japanese Patent JP2008505146
Kind Code:
A
Abstract:
A D-Xylopyranosyl-substituted phenyl compound of general formula I wherein the groups R1 to R5, X, Z and R7a, R7b, R7c are defined as in claim 1, have an inhibiting effect on the sodium-dependent glucose cotransporter SGLT. The present invention also relates to pharmaceutical compositions for the treatment of metabolic disorders.
Inventors:
Eckhart Matthias
Himmelsbach Frank
Eikermann Peter
Thomas Leo
Berthomian Edward Leon
Himmelsbach Frank
Eikermann Peter
Thomas Leo
Berthomian Edward Leon
Application Number:
JP2007519682A
Publication Date:
February 21, 2008
Filing Date:
June 30, 2005
Export Citation:
Assignee:
Boehringer Ingelheim International GmbH
International Classes:
C07D309/10; A61K31/351; A61K31/70; A61P3/04; A61P3/06; A61P3/08; A61P3/10; A61P7/10; A61P9/04; A61P9/10; A61P9/12; A61P19/06; A61P43/00; C07H7/04; C07H15/203
Domestic Patent References:
| JP2004359630A | 2004-12-24 | |||
| JP2004359630A | 2004-12-24 |
Foreign References:
| WO2002083066A2 | 2002-10-24 | |||
| WO2005092877A1 | 2005-10-06 | |||
| WO1998031697A1 | 1998-07-23 | |||
| WO1998031697A1 | 1998-07-23 | |||
| WO2002083066A2 | 2002-10-24 | |||
| WO2005092877A1 | 2005-10-06 |
Other References:
JPN6011055392; Ｓｙｎｌｅｔｔ Ｎｏ．６, 1999, ７３７-７４０
JPN6011055390; Ｂｉｏｃｈｉｍｉｃａ ｅｔ Ｂｉｏｐｈｙｓｉｃａ Ａｃｔａ １３３５, 1997, ６１-７２
JPN6011055390; Ｂｉｏｃｈｉｍｉｃａ ｅｔ Ｂｉｏｐｈｙｓｉｃａ Ａｃｔａ １３３５, 1997, ６１-７２
JPN6011055392; Ｓｙｎｌｅｔｔ Ｎｏ．６, 1999, ７３７-７４０
JPN6011055390; Ｂｉｏｃｈｉｍｉｃａ ｅｔ Ｂｉｏｐｈｙｓｉｃａ Ａｃｔａ １３３５, 1997, ６１-７２
JPN6011055390; Ｂｉｏｃｈｉｍｉｃａ ｅｔ Ｂｉｏｐｈｙｓｉｃａ Ａｃｔａ １３３５, 1997, ６１-７２
JPN6011055392; Ｓｙｎｌｅｔｔ Ｎｏ．６, 1999, ７３７-７４０
Attorney, Agent or Firm:
Sadao Kumakura
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama
Nobuo Ogawa
Atsushi Hakoda
Kenji Asai
Koji Hirayama