Title:
DICYCLIC COMPOUNDS
Document Type and Number:
Japanese Patent JPS52142092
Kind Code:
A
Abstract:
Derivatives of 5-norbicyclomycin of the formula wherein R represents an unsubstituted or substituted monovalent hydrocarbon radical in which one, two or more carbon atoms can be replaced by heteroatoms, and X represents a bivalent group of the formula -O- or -N(R')-, wherein R' has one of the meanings assigned to R, whilst R and R', if both have a meaning which is different from hydrogen, can also be linked to each other through a C-C bond or an oxygen, sulphur or nitrogen atom, and corresponding compounds, in which at least one hydroxyl group is protected, and salts of said compounds, provided they contain salt-forming groups, are useful as antibiotics, especially against Enterobacteriaceae, or as intermediates for the production of such antibiotics. They are obtained by condensing a corresponding 5-norbicyclomycin-5-one with a compound of the formula R-X-NH2 in which X and R have the above meaning.
Inventors:
BEATO MIYURURA
BUIRUHERUMU KUMUPU
OSUKARU BUATSUKERU
BUIRUHERUMU KUMUPU
OSUKARU BUATSUKERU
Application Number:
JP5781877A
Publication Date:
November 26, 1977
Filing Date:
May 20, 1977
Export Citation:
Assignee:
CIBA GEIGY AG
International Classes:
C07D498/08; A61K31/505; A61P31/04; C07H9/06; (IPC1-7): A61K31/505; C07D498/08
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