Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
EXTRACTION OF HEMOSTATIC SUBSTANCE FROM "SOKUHAKUYO" AND HEMOSTAT CONTAINING THE SAME
Document Type and Number:
Japanese Patent JPS60193996
Kind Code:
A
Abstract:

PURPOSE: An aqueous extract of leaves of SOKUHAKU (Thujae orientalis cacumen) is extracted with an organ ic solvent, then subjected to gel-filtration column chromatography and chromatography to effect siolation and purification to obtain simply quercitrin which is used as a hemostatic.

CONSTITUTION: Leaves of SOKUHAKU is extracted with hot water and the extract is fractionated with an ethyl acetate-water solvent mix system and the ethyl acetate phase is separated. The resultant lipid-soluble substances are separated by means of gel-filtration column chromatography using methanol as a eluent to collect the hemostatic fractions. Further, the fractions are purified by subjecting them to silica-gel chromatography and gel-filtration column chromatography to obtain the objective quercitrin.


Inventors:
KOSUGE TAKUO
ISHIDA KINJI
ITOU YASUO
KATOU HIDEO
Application Number:
JP4717184A
Publication Date:
October 02, 1985
Filing Date:
March 14, 1984
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
HOKURIKU PHARMACEUTICAL
International Classes:
C07H17/07; A61K31/70; A61K31/7042; A61K31/7048; A61K36/00; A61P7/04; (IPC1-7): A61K31/70; A61K35/78; C07H17/07