Title:
ＧＲＰＲ陽性ガンの検出、診断及び治療のためのＧＲＰＲアンタゴニスト
Document Type and Number:
Japanese Patent JP6997135
Kind Code:
B2
Abstract:
The present invention relates to probes for use in the detection, imaging, diagnosis, targeting, treatment, etc. of cancers expressing the gastrin releasing peptide receptor (GRPR). For example, such probes may be molecules conjugated to detectable labels which are preferably moieties suitable for detection by gamma imaging and SPECT or by positron emission tomography (PET) or magnetic resonance imaging (MRI) or fluorescence spectroscopy or optical imaging methods.
Inventors:
Shiodosia Mina-Knock
Berthold Archer Knock
Marion De Jong Hendricks
Berthold Archer Knock
Marion De Jong Hendricks
Application Number:
JP2019104379A
Publication Date:
February 04, 2022
Filing Date:
June 04, 2019
Export Citation:
Assignee:
Advanced Accelerator Applications USA, Inc.
International Classes:
C07K7/06; A61K47/64; A61K51/08; A61P1/00; A61P1/18; A61P11/00; A61P13/08; A61P13/12; A61P15/00; A61P17/00; A61P25/00; A61P35/00; A61P43/00
Domestic Patent References:
| JP6562838B2 | ||||
| JP2006528644A | ||||
| JP2250898A | ||||
| JP4502629A |
Foreign References:
| US5028692 | ||||
| US5019647 | ||||
| US5620955 |
Other References:
Clinical Cancer Researech,2009年,Vol.15, No.16,p.5240-5249
Chemistry A European Journal,2010年,Vol.16,p.2115-2124
Journal of Medicinal Chemistry,1991年,Vol.34,p.2102-2107
Bioconjugate Chemistry,2008年,Vol.19,p.2040-2048
Chemistry A European Journal,2010年,Vol.16,p.2115-2124
Journal of Medicinal Chemistry,1991年,Vol.34,p.2102-2107
Bioconjugate Chemistry,2008年,Vol.19,p.2040-2048
Attorney, Agent or Firm:
Murayama Yasuhiko
Shinya Mihiro
Tatsuhiko Abe
Shinya Mihiro
Tatsuhiko Abe