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Title:
GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR TREATMENT OF DISEASES
Document Type and Number:
Japanese Patent JP2019182869
Kind Code:
A
Abstract:
To provide novel methods for treating or preventing diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).SOLUTION: Described herein are compounds of formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions associated with the enzyme glucosylceramide synthase (GCS).SELECTED DRAWING: None

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Inventors:
BING WANG
CHU DANIEL
ALEXANDER JAMES BRIDGES
Application Number:
JP2019104161A
Publication Date:
October 24, 2019
Filing Date:
June 04, 2019
Export Citation:
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Assignee:
BIOMARIN PHARM INC
International Classes:
C07D205/04; A61K31/397; A61K31/4025; A61K31/404; A61K31/4155; A61K31/416; A61K31/4184; A61K31/423; A61K31/427; A61K31/428; A61K31/437; A61K31/4439; A61K31/46; A61K31/4709; A61K31/497; A61K31/498; A61K31/5377; A61P3/06; A61P3/10; A61P9/10; A61P13/12; A61P25/00; A61P29/00; A61P31/00; A61P35/00; C07D207/27; C07D209/24; C07D211/34; C07D211/46; C07D213/30; C07D213/56; C07D213/61; C07D213/64; C07D215/12; C07D215/14; C07D231/04; C07D231/12; C07D231/56; C07D235/08; C07D249/06; C07D277/587; C07D277/593; C07D277/62; C07D295/13; C07D305/08; C07D307/81; C07D307/91; C07D309/12; C07D319/18; C07D319/20; C07D333/24; C07D333/60; C07D333/62; C07D401/06; C07D401/12; C07D405/06; C07D405/12; C07D405/14; C07D407/12; C07D409/12; C07D413/12; C07D417/12; C07D451/04; C07D471/04; C07D487/08; C07D491/044; C07D491/056; C07D498/04
Domestic Patent References:
JP2010540638A2010-12-24
JP2012504608A2012-02-23
JP2011529500A2011-12-08
JP2013032377A2013-02-14
Foreign References:
WO2008150486A22008-12-11
WO2009117150A22009-09-24
US20130095089A12013-04-18
Attorney, Agent or Firm:
Toru Ishikawa



 
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