Title:
組織工学腱及びその生体外構築方法
Document Type and Number:
Japanese Patent JP2010531683
Kind Code:
A
Abstract:
The invention discloses a tissue engineering graft, comprising:(a) pharmaceutically-acceptable biodegradable material; and (b) seed cells, which can be inoculated on the described biodegradable material and are selected from:(i) fibroblasts; (ii) adipose derived cells, or (iii) mixture of dermal fibroblasts and ASCs according to the ratio of 1:10000-10000:1. The graft can be prepared by mixing of seed cell and pharmaceutically-acceptable biodegradable material, obtaining a construct of seed cells and pharmaceutically-acceptable biodegradable material, then culturing the construct in a bioreactor in vitro. The graft can be used for repairing the defect of tendon tissues.
Inventors:
Cao Yu Forest
Liu Wei
Hu Peak
Don Tan
Li Hong
Choi
Liu Wei
Hu Peak
Don Tan
Li Hong
Choi
Application Number:
JP2010513625A
Publication Date:
September 30, 2010
Filing Date:
March 24, 2008
Export Citation:
Assignee:
Shanghai Guo Life Science and Technology Co., Ltd.
NO.9 PEOPLE HOSPITAL AFFILIATED TO SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
NO.9 PEOPLE HOSPITAL AFFILIATED TO SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
International Classes:
A61L27/00; A61K35/12; A61K35/32; A61P19/00; A61P19/04; C12N5/071; C12N5/077
Domestic Patent References:
| JP2009523494A | 2009-06-25 | |||
| JP2005529631A | 2005-10-06 |
Foreign References:
| CN1507926A | 2004-06-30 | |||
| WO2007030811A2 | 2007-03-15 | |||
| WO2006048783A2 | 2006-05-11 |
Attorney, Agent or Firm:
Kuro Fukami
Toshio Morita
Yoshihei Nakamura
Yutaka Horii
Masayuki Sakai
Nobuo Arakawa
Masato Sasaki
Toshio Morita
Yoshihei Nakamura
Yutaka Horii
Masayuki Sakai
Nobuo Arakawa
Masato Sasaki