Title:
HETEROCYCLIC COMPOUND AND ITS ACID ADDITION SALT
Document Type and Number:
Japanese Patent JPS5549386
Kind Code:
A
Abstract:
NEW MATERIAL:A heterocyclic compound of formula I (R1 is H, lower alkyl, etc.; R2,3 are H, aryl, etc., or a group which forms a benzene ring by cyclization), and its acid addition salt.
EXAMPLE: 7-Ethoxycarbonyl-2-phenyl-5, 6, 7, 8-tetrahydroimidazo[2', 1':2, 3] thiazolo [5, 4-c]-pyridine hydrobromide.
USE: Medicine or its intermediate, having antiphlogistic, antirheumatic, immuno- suppressing, antibacterial, analgesic and carcinostatic activities.
PROCESS: 5, 6, 7, 8-Tetrahydroimidazo[2', 1:2, 3]thiazolo[5, 4-c]pyridine compound of formula IV is prepared by reacting a compound II with a compound III (X is halogen) in an inert solvent pref. an alcohol or its mixture, at a temperature between room temperature and about 200°C.
Inventors:
MUNAKATA TOMOHIKO
SAEKI SUMI
GOTOU KAZUHIRO
IKEGAMI KIYOTERU
SAEKI SUMI
GOTOU KAZUHIRO
IKEGAMI KIYOTERU
Application Number:
JP12303478A
Publication Date:
April 09, 1980
Filing Date:
October 04, 1978
Export Citation:
Assignee:
YOSHITOMI PHARMACEUTICAL
International Classes:
C07D513/14; A61K31/425; A61P25/04; A61P29/00; A61P31/04; A61P35/00; A61P37/06; C07D513/22; C07D515/22; (IPC1-7): A61K31/425; C07D513/14; C07D515/22