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Title:
HMB COMPOSITIONS AND USES THEREOF
Document Type and Number:
Japanese Patent JP2015147773
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss.SOLUTION: Patients are enterally administered β-hydroxy-β-methylbutyrate (HMB) alone or alternatively in combination with eicosapentaenoic acid (20:5;ω-3), carnitine and mixtures thereof. HMB may be added to food products comprising a source of amino-nitrogen enriched with large neutral amino acids such as leucine, isoleucine, valine, tyrosine, threonine and phenylalanine and substantially lacking in free amino acids.

Inventors:
BAXTER JEFFREY H
MUKERJI PRADIP
ANNE C VOSS
TISDALE MICHAEL J
Application Number:
JP2015045519A
Publication Date:
August 20, 2015
Filing Date:
March 09, 2015
Export Citation:
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Assignee:
ABBOTT LAB
International Classes:
A61K31/19; A23L1/30; A61K31/197; A61K31/202; A61K31/205; A61K31/702; A61P1/12; A61P1/16; A61P3/02; A61P11/00; A61P13/12; A61P19/02; A61P31/00; A61P35/00
Domestic Patent References:
JP2001288107A2001-10-16
JP2003137790A2003-05-14
JP2002518440A2002-06-25
JPH07507569A1995-08-24
JP2002521428A2002-07-16
JPH09121809A1997-05-13
JPH11508282A1999-07-21
Foreign References:
WO1998004253A11998-02-05
US4742081A1988-05-03
Other References:
AMERICAN JOURNAL OF SURGERY, vol. V183 N4, JPN5007004234, April 2002 (2002-04-01), pages 471 - 479, ISSN: 0003236121
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, vol. 24, no. 3, JPN5007004235, May 2000 (2000-05-01), pages 133 - 9, ISSN: 0003236122
RES. COMM. MOL. PATH. PHARM., vol. 111(1-4), JPN6016034672, 2002, pages 139 - 52, ISSN: 0003395576
RES. COMM. MOL. PATH. PHARM., vol. 113,114, JPN6016034673, 2003, pages 159 - 70, ISSN: 0003395577
Attorney, Agent or Firm:
Kawaguchi International Patent Office