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Title:
光シート顕微鏡および試料を光学顕微鏡で結像する方法
Document Type and Number:
Japanese Patent JP7003065
Kind Code:
B2
Abstract:
A light sheet microscope includes an illumination optical system configured to generate a light sheet in an intermediate image space. A transport optical system, which is telecentric on both sides, is configured to image the light sheet generated in the intermediate image space into a sample and to image a region of the sample illuminated by the light sheet as an intermediate image into the intermediate image space. A detection optical system is configured to image the intermediate image generated in the intermediate image space onto a detector. The optical axes of the illumination optical system, the transport optical system and the detection optical system intersect one another in the intermediate image space. The microscope further includes a scanning element, which is arranged in the transport optical system and through which the light sheet is moveable in the sample transversely to the optical axis of the transport optical system.

Inventors:
Christian Schumann
Application Number:
JP2018562708A
Publication Date:
January 20, 2022
Filing Date:
February 21, 2017
Export Citation:
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Assignee:
Leica Microsystems CMS GmbH
International Classes:
G02B21/00; G02B21/06; G02B21/36
Domestic Patent References:
JP2016001274A
JP2013506150A
Foreign References:
US20110261446
US5192980
Other References:
Sunil Kumar ET AL,"HIGH-SPEED 2D AND 3D FLUORESCENCE MICROSCOPY OF CARDIAC MYOCYTES",OPTICS EXPRESS,2011年07月06日,Vol.19, No.15,PAGE(S):13839-138747,https://www.osapublishing.org/DirectPDFAccess/C96AC319-FDB4-0A24-822F23D70437C5F5_219582/oe-19-15-13839.pdf?da=1&id=219582&seq=0&mobile=no
Attorney, Agent or Firm:
Einzel Felix-Reinhard
Taku Morita
Junichi Maekawa
Hiroyasu Ninomiya
Ueshima class