Title:
６－アミノイソキノリンを調製する方法
Document Type and Number:
Japanese Patent JP7082980
Kind Code:
B2
Abstract:
Described are methods for the preparation of 6-aminoisoquinoline, a useful intermediate compound in the synthesis of kinase inhibitors.
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Inventors:
Chambournier, Jill
Delong, Mitchell Ay
Delong, Mitchell Ay
Application Number:
JP2019535803A
Publication Date:
June 09, 2022
Filing Date:
December 11, 2017
Export Citation:
Assignee:
Aerie Pharmaceuticals Incorporated
International Classes:
C07D217/22
Domestic Patent References:
| JP1503233A | ||||
| JP2005510564A |
Foreign References:
| WO2003080578A1 | ||||
| WO2016123627A1 | ||||
| CN105017152A |
Other References:
Sturdivant, Jill M.; DeLong, Mitchell A.,Identification of intermediates in the stepwise reduction of 1, 3-dichloro-6-nitroisoquinoline to 6-aminoisoquinoline,Abstracts of Papers, 248th ACS National Meeting & Exposition, San Francisco, CA, United States, August 10-14, 2014,2014年,MEDI-153
日本化学会,新実験化学講座1 基本操作I,1985年06月10日,P318-325
Fox, Mark A.; Pattison, Graham; Sandford, Graham; Batsanov, Andrei S.,19F and 13C GIAO-NMR chemical shifts for the identification of perfluoro-quinoline and -isoquinoline derivatives,Journal of Fluorine Chemistry ,2013年,155,62-71
Tsou, Hwei-Ru 他 ,4-(Phenylaminomethylene)isoquinoline-1,3(2H,4H)-diones as Potent and Selective Inhibitors of the Cyclin-Dependent Kinase 4 (CDK4),Journal of Medicinal Chemistry ,2008年,51(12),3507-3525
Perner, Richard J.; DiDomenico, Stanley; Koenig, John R.; Gomtsyan,In vitro structure-activity relationship and in vivo characterization of 1-(aryl)-3-(4-(amino)benzyl)urea transient receptor potential vanilloid 1 antagonists,Journal of Medicinal Chemistry ,2007年,50(15),3651-3660
日本化学会,新実験化学講座1 基本操作I,1985年06月10日,P318-325
Fox, Mark A.; Pattison, Graham; Sandford, Graham; Batsanov, Andrei S.,19F and 13C GIAO-NMR chemical shifts for the identification of perfluoro-quinoline and -isoquinoline derivatives,Journal of Fluorine Chemistry ,2013年,155,62-71
Tsou, Hwei-Ru 他 ,4-(Phenylaminomethylene)isoquinoline-1,3(2H,4H)-diones as Potent and Selective Inhibitors of the Cyclin-Dependent Kinase 4 (CDK4),Journal of Medicinal Chemistry ,2008年,51(12),3507-3525
Perner, Richard J.; DiDomenico, Stanley; Koenig, John R.; Gomtsyan,In vitro structure-activity relationship and in vivo characterization of 1-(aryl)-3-(4-(amino)benzyl)urea transient receptor potential vanilloid 1 antagonists,Journal of Medicinal Chemistry ,2007年,50(15),3651-3660
Attorney, Agent or Firm:
Kimura Mitsuru
Yasushi Morikawa
Kei Sakurada
Hideki Mie
Yasushi Morikawa
Kei Sakurada
Hideki Mie
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