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Title:
水酸基保護試薬およびそれを用いた水酸基の保護方法
Document Type and Number:
Japanese Patent JP4624923
Kind Code:
B2
Abstract:
The present invention relates to a method of protecting a hydroxyl group, which includes reacting a hydroxyl group-containing compound with a compound represented by the formula (I) : wherein R is a phenyl group optionally having substituent(s), an alkyl group optionally having substituent(s) or a benzyl group optionally having substituent(s), and X is a halogen atom, in the presence of an acid catalyst to substitute the hydrogen atom of the hydroxyl group of the hydroxyl group-containing compound with a protecting group represented by the formula (II): wherein R is as defined above. The present invention provides a method capable of introducing an acetal type protecting group into a hydroxyl group under mild conditions, and a protecting reagent therefor and a method of producing the protecting reagent.

Inventors:
Tetsuya Ikemoto
Yosuke Watanabe
Application Number:
JP2005512906A
Publication Date:
February 02, 2011
Filing Date:
June 23, 2004
Export Citation:
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Assignee:
Sumitomo Chemical Co., Ltd.
International Classes:
C07B51/00; C07B41/04; C07C41/14; C07C43/166; C07C43/174; C07C67/31; C07C67/343; C07C69/708; C07D307/32; C07B61/00
Other References:
Lilia M. BEAUCHAMP et al.,Journal of Medicinal Chemistry ,1988年,vol.31 no.1,pp.144-149
Xue-Ping GU et al.,The Journal of Organic Chemistry ,1987年,52(15),pp.3192-3196
Attorney, Agent or Firm:
Takashima Ichi



 
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