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Patent Searching and Data


Title:
HYDROXYLAMINE COMPOUND
Document Type and Number:
Japanese Patent JPH04224552
Kind Code:
A
Abstract:

PURPOSE: To provide a new hydroxylamine compound having strong specific inhibiting activity on the enzyme ornithine decarboxylase, that is, anti-growth property.

CONSTITUTION: A compound of formula I [R1 is amino or formula II (R3 is an alkyl, hydroxyalkyl, alkoxyalkyl, phenyl, etc.; R4 is H, an alkyl, etc., or R3 and R4 form an alkylene or benzoalkylene together); R2 is an alkyl], or a salt thereof, e.g. N-(3-aminoxy-2-fluoropropyl)-methylamino dihydrochloric acid salt. The compound of the formula I is prepared by reacting, e.g. a compound of formula III (Y is a group which is optionally substituted into F or is optionally substituted by F), with a fluorinating agent.


Inventors:
YAROSURAFU SHIYUTANETSUKU
IERUKU FURAI
Application Number:
JP7787391A
Publication Date:
August 13, 1992
Filing Date:
April 10, 1991
Export Citation:
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Assignee:
CIBA GEIGY AG
International Classes:
A61K31/15; C07C239/20; C07C251/58; C07D213/59; C12N9/99; A61K31/13; (IPC1-7): A61K31/13; A61K31/15; C07C239/20; C07C251/58; C07D213/59; C12N9/99
Attorney, Agent or Firm:
Aoki Akira (3 outside)