Title:
Inhibitor of a fibroblast growth factor receptor
Document Type and Number:
Japanese Patent JP6104377
Kind Code:
B2
Abstract:
Described herein are inhibitors of FGFR, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions to inhibit the activity of tyrosine kinases.
Inventors:
Bifurco, Neil Junior
Blue geance, natasha
Hodus, Brian El.
Kim, Joseph El.
Midudul, Chandrasekhar buoy.
Wen Growski, Stephen Mark
Blue geance, natasha
Hodus, Brian El.
Kim, Joseph El.
Midudul, Chandrasekhar buoy.
Wen Growski, Stephen Mark
Application Number:
JP2015521815A
Publication Date:
March 29, 2017
Filing Date:
July 11, 2013
Export Citation:
Assignee:
Blueprint Medicines Corporation
International Classes:
A61K31/4375; C07D239/84; A61K31/517; A61K31/519; A61K31/5377; A61P3/06; A61P25/00; C07D471/04; C07D475/00; C07D487/04
Domestic Patent References:
| JP2004519422A | ||||
| JP2012501654A | ||||
| JP2011526299A | ||||
| JP2014513729A |
Foreign References:
| WO2004063195A1 | ||||
| WO2011034907A1 |
Other References:
CHEMISTRY AND BIOLOGY,英国,2010年 3月26日,V17 N3,P285-295
Journal of Medicinal Chemistry,2012年,55(5),2251-2264
Journal of Medicinal Chemistry,2011年,54(5),1347-1355
Bioorganic & Medicinal Chemistry Letters,2009年,19(24),6872-6876
Journal of Medicinal Chemistry,2012年,55(5),2251-2264
Journal of Medicinal Chemistry,2011年,54(5),1347-1355
Bioorganic & Medicinal Chemistry Letters,2009年,19(24),6872-6876
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto