Title:
ヒトアルドステロン合成酵素ＣＹＰ１１Ｂ２の阻害剤
Document Type and Number:
Japanese Patent JP5652918
Kind Code:
B2
Abstract:
The invention provides compounds of the general formula (I) which are inhibitors of the human aldosterone synthase, and also pharmaceutical compositions containing these compounds, and the use of these compounds and other heteroaryl substituted quinolinone derivatives for the treatment of hyperaldosteronism and/or disorders or diseases that are mediated by 11 β-hydroxylase (CYP11 B1).
Inventors:
ハルトマン，ロルフ ベー．
ハイム，ラルフ
ルカス，ジモン
ハイム，ラルフ
ルカス，ジモン
Application Number:
JP2011507827A
Publication Date:
January 14, 2015
Filing Date:
May 05, 2009
Export Citation:
Assignee:
エレクソファーム ゲゼルシャフト ミット ベシュレンクテル ハフツング
International Classes:
C07D401/04; A61K31/437; A61K31/4439; A61K31/444; A61K31/4709; A61K31/4725; A61K31/498; A61K31/4985; A61K31/506; A61K31/519; A61K31/536; A61K31/5365; A61K31/538; A61K31/5383; A61K31/5415; A61K31/542; A61K31/548; A61P3/04; A61P5/42; A61P7/00; A61P7/10; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P29/00; C07D413/04; C07D417/04; C07D455/04; C07D471/06; C07D487/04; C07D487/06; C07D498/04; C07D498/06; C07D513/04; C07D513/06
Attorney, Agent or Firm:
Aoki 篤
Ishida 敬
Tsumoru Fukumoto
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Kazumi Nakamura
Ishida 敬
Tsumoru Fukumoto
Tetsuji Koga
Yoichi Watanabe
Ryotaro Takei
Kazumi Nakamura