Title:
【発明の名称】L-リボース誘導体
Document Type and Number:
Japanese Patent JP2843592
Kind Code:
B2
Abstract:
A process of preparing l -biopterin is disclosed which comprises the steps of: Subjecting to selective Grignard reaction D-ribose having the hydroxyl groups in the 2- and 3-positions protected by an acetal group to give 6-deoxy-3,4-O-alkylidene allitol; subjecting the 1- and 2-positions of said allitol to oxidative cleavage to form 5-deoxy-2,3-O-alkylidene-L-ribose followed by deacetalization to give 5-deoxy-L-ribose; reacting 5-deoxy-L-ribose with a hydrazine compound to form a 5-deoxy-L-ribose hydrazone compound; and subjecting said hydrazone compound to condensation reaction with an acid addition salt of 4-hydroxy-2,5,6-triaminopyrimidine followed by oxidation.
Inventors:
KIKUCHI HARUHIKO
MORI KENJI
MORI KENJI
Application Number:
JP4535789A
Publication Date:
January 06, 1999
Filing Date:
February 28, 1989
Export Citation:
Assignee:
NITSUSHIN SEIFUN KK
International Classes:
C07D475/04; C07H5/04; C07H9/04; C07H15/203; (IPC1-7): C07H5/04; C07D475/04
Attorney, Agent or Firm:
Chika Takagi (2 outside)