Title:
MANUFACTURE OF SMALL BENZOYL PEROXIDE CRYSTAL
Document Type and Number:
Japanese Patent JPS5869863
Kind Code:
A
Abstract:
There is disclosed a process for producing benzoyl peroxide in crystalline form with crystals having a size of up to approximaely 10 microns, comprising:
forming a first solution comprising benzoyl peroxide and a precipitate-promoting material selected from sulphur-containing aliphatic ethers, long-chain aliphatic and araliphatic ethers, ethylene oxide derivatives, and mixtures thereof;
mixing the first solution with a second solution comprising an aqueous solution of a non-toxic and non-reactive dispersant selected from cellulosic derivatives, anionic surfactants, non-ionic surfactants, inorganic colloidal materials, and mixtures thereof: and
recovering the benzoyl peroxide in the desired crystalline form.
The process may be performed at room temperature and is therefore safe and energy conservative. The resulting benzoyl peroxide crystals are of desirable small size, and are particularly well suited for incorporation into commercial cosmetic and pharmaceutical preparations.
Inventors:
AASAA TARAASOBU
Application Number:
JP16111882A
Publication Date:
April 26, 1983
Filing Date:
September 17, 1982
Export Citation:
Assignee:
WARNER LAMBERT CO
International Classes:
A61K8/30; A61K8/33; C07C67/00; A61K31/19; C07C407/00; C07C409/32; C07C409/34; C07C409/36; (IPC1-7): A61K7/00; A61K31/19; C07C179/14
Attorney, Agent or Firm:
Tatsuo Sato