Title:
MEDICINE AGAINST ACQUIRED IMMUNE DYSFUNCTION SYNDROME AIDS
Document Type and Number:
Japanese Patent JPS63107936
Kind Code:
A
Abstract:
1. 3'-fluorinated pyrimidine or purine nucleosides of the general formula I see diagramm : EP0254268,P10,F1 wherein R**1 denotes an N-1-glycosidically bonded radical which is derived from thymine, from uracil, from a 5-substituted uracil, from cytosine or from a 5-substituted cytosine derivative, or an N-9-glycosidically bonded radical which is derived from 2-fluoroadenine, from 2,6-diaminopurine, from 2-aminopurine, from 6-thioguanine or from 7-deazadenine, R**2 denotes H or OH and R**3 denotes OH, O-acetyl, O-palmitoyl, triphosphate as a free acid or in the form of corresponding alkali metal, ammonium or alkylammonium salts or a precursor group for the hydroxyl, with the exception of those compounds of the formula I in which R**1 denotes an N-1-glycosidically bonded radical which is derived from thymine, from uracil, from a 5-substituted uracil, from cytosine or from a 5-substituted cytosine derivative, R**2 denotes H and R**3 denotes OH.
Inventors:
ETSUKARUTO MATSUTOHESU
KURISUTEINE REEMAN
DEIITERU SHIYORUTSU
MARUTEIN FUON YANTAARIPINSUKII
KURAUSU GERUTONERU
PEETERU RANGEN
HANSU ARUFUREETO ROOZENTAARU
KURISUTEINE REEMAN
DEIITERU SHIYORUTSU
MARUTEIN FUON YANTAARIPINSUKII
KURAUSU GERUTONERU
PEETERU RANGEN
HANSU ARUFUREETO ROOZENTAARU
Application Number:
JP18242387A
Publication Date:
May 12, 1988
Filing Date:
July 23, 1987
Export Citation:
Assignee:
AKAD WISSENSCHAFTEN DDR
International Classes:
A61K9/00; A61K31/505; A61K31/70; A61K31/7042; A61K31/7052; A61K31/7064; C07H19/073; A61K31/7068; A61K31/7072; A61K31/7076; A61P31/12; A61P31/18; C07H17/00; C07H19/06; C07H19/09; C07H19/14; C07H19/16; C07H19/173; C07H19/19; (IPC1-7): A61K31/70; C07H19/073; C07H19/09; C07H19/14; C07H19/173; C07H19/19
Domestic Patent References:
| JPS64500193A |
Attorney, Agent or Firm:
Akira Asamura (3 outside)