To provide a method for monoarylating a dicarboximide compound, by which only one aryl group can extremely simply be introduced into the carbonyl group of the dicarboximide compound.
This method for monoarylating a dicarboximide compound represented by formula (2) (the ring A is a benzene ring, a naphthalene ring or a heterogeneous ring which may be substituted by one or more arbitrary functional groups; R1 and R2 are each a lower alkyl; Ar is an aryl which may be substituted by one or more arbitrary functional groups), characterized by reacting a dicarboximide compound represented by formula (1) with a compound of the formula: Ar-H in the presence of a Lewis acid. A condensed pyridazinone compound useful as a medicine can easily be produced from the obtained compound.
SAKAMOTO TAKESHI
SAITO YUKO
