Title:
ラクトバチルス・プランタラムの培養物の製造方法
Document Type and Number:
Japanese Patent JP7057059
Kind Code:
B2
Abstract:
Provided is a method of producing a culture product of a microorganism, for obtaining a culture product excellent in anti-inflammatory property in which a ratio between the production amounts of IL-10 and IL-12 (ratio of IL-10/IL-12) is large. Specifically, provided is a method of producing a culture product of Lactobacillus plantarum, including culturing Lactobacillus plantarum using a medium containing an unsaturated fatty acid ester until a time point at or before an end of a logarithmic growth phase, to thereby obtain a culture product of Lactobacillus plantarum. The unsaturated fatty acid ester is an ester formed through a reaction between a monovalent or polyvalent unsaturated fatty acid and a polyhydric alcohol, or a derivative of the ester. A preferred example of the unsaturated fatty acid ester is a monooleic acid ester.
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Inventors:
Keisuke Furuichi
Takayuki Toshimitsu
Satoru Ozaki
Takayuki Toshimitsu
Satoru Ozaki
Application Number:
JP2016162010A
Publication Date:
April 19, 2022
Filing Date:
August 22, 2016
Export Citation:
Assignee:
Meiji Co., Ltd.
International Classes:
C12N1/38; A23L33/135; A61K35/747; A61P1/04; A61P3/00; A61P9/00; A61P25/00; A61P29/00; A61P35/00; A61P37/02; A61P37/06; A61P43/00; C12N1/00; C12N1/20; C12Q1/02
Domestic Patent References:
| JP2013502456A | ||||
| JP2011250756A |
Other References:
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TOSHIMITSU, T. et al.,Appl. Environ. Microbiol.,2017年,Vol.83, No.7,e03001-16(pp.1-13)
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LEBEER, S. et al.,Microbiol. Mol. Biol. Rev.,2008年,Vol.72, No.4,pp.728-764
SHIRAISHI, T. et al.,Biosci. Microbiota Food Health,2016年06月,Vol.35, No.4,pp.147-161
VAN BAARLEN, P. et al.,Proc. Natl. Acad. Sci. USA,2009年,Vol.106, No.7,pp.2371-2376
VEERKAMP, J.H.,J. Bacteriol.,1971年,Vol.108, No.2,pp.861-867
TOSHIMITSU, T. et al.,J. Daily Sci.,2016年02月,Vol.99,pp.933-946
STEVENS, M.J.A. et al.,Appl. Environ. Microbiol.,2008年,Vol.74, No.15,pp.4776-4778
DE MAN, J.C. et al.,J. Appl. Bacteriol.,1960年,Vol.23, No.1,pp.130-135
MRS Broth (Lactosebacillus Broth acc. to DE MAN, ROGOSA and SHARPE), Merck Microbiology Manual 12th Edition, p.356,,メルクミリポアWebサイト,2021年06月28日,https://www.merckmillipore.com/JP/ja/product/MRS-broth,MDA_CHEM-110661#documentation,[retrieved on 2021-06-28], Retrieved from the Internet
KAJI, R. et al.,J. Immunol.,2010年,Vol.184,pp.3505-3513
KIM, H.G. et al.,FEMS Immunol. Med. Microbiol.,2007年,Vol.49,pp.205-214
KIM, H.G. et al.,J. Immunol.,2008年,Vol.180,pp.2553-2561
TAKEDA, K. and AKIRA, S.,Jpn. J. Infect. Dis.,2001年,Vol.54,pp.209-219
BLOKSMA, N. et al.,Clin. Exp. Immunol.,1979年,Vol.37,pp.367-375
TOSHIMITSU, T. et al.,Appl. Environ. Microbiol.,2017年,Vol.83, No.7,e03001-16(pp.1-13)
GRANGETTE, C. et al.,Proc. Natl. Acad. Sci. USA,2005年,Vol.102, No.29,pp.10321-10326
JANG, K.-S.,Biochem. Biophys. Res. Commun.,2011年,Vol.407,pp.823-830
SHIRAISHI, T. et al.,Appl. Environ. Microbiol.,2013年,Vol.79, No.10,pp.3315-3318,AUTHER'S CORRECTION(Vol.79, No.24, p.7931)
JOHNSSON, T. et al.,Appl. Environ. Microbiol.,1995年,Vol.61, No.12,pp.4497-4499
LEBEER, S. et al.,Microbiol. Mol. Biol. Rev.,2008年,Vol.72, No.4,pp.728-764
SHIRAISHI, T. et al.,Biosci. Microbiota Food Health,2016年06月,Vol.35, No.4,pp.147-161
Attorney, Agent or Firm:
Hokuta Naoyuki
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