Title:
METHOD FOR PRODUCING N4-PHENYL-QUINAZOLINE-4-AMINE DERIVATIVE, AND INTERMEDIATE THEREOF
Document Type and Number:
Japanese Patent JP2010270154
Kind Code:
A
Abstract:
To provide a compound which inhibits type I receptor tyrosine kinase, and is useful for treating hyperproliferative disorders such as cancer and inflammation in mammals, particularly in human.
The compound useful as a type I receptor tyrosine kinase inhibitor is expressed by formula I. A pharmaceutical composition including the compound and a method of producing the compound are also provided.
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Inventors:
LYSSIKATOS JOSEPH P
MARMSAETER FREDRIK P
ZHAO QIAN
GRESCHUK JULIE MARIE
LUI WEIDONG
HENNINGS DAVID D
MARMSAETER FREDRIK P
ZHAO QIAN
GRESCHUK JULIE MARIE
LUI WEIDONG
HENNINGS DAVID D
Application Number:
JP2010198848A
Publication Date:
December 02, 2010
Filing Date:
September 06, 2010
Export Citation:
Assignee:
ARRAY BIOPHARMA INC
International Classes:
C07D401/14; A61K31/517; A61K31/519; A61K31/5377; A61K31/541; A61P43/00; C07D403/12; C07D403/14; C07D405/14; C07D413/12; C07D413/14; C07D417/12; C07D417/14; C07D471/04; C07D495/04; C07D519/00; A61P1/04; A61P1/18; A61P3/10; A61P9/04; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P11/12; A61P17/00; A61P17/06; A61P19/00; A61P19/02; A61P19/04; A61P25/28; A61P27/02; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P35/02; A61P37/06; A61P37/08
Domestic Patent References:
JP2005515176A | 2005-05-26 | |||
JP2004517059A | 2004-06-10 | |||
JP2002544196A | 2002-12-24 | |||
JP2007502786A | 2007-02-15 | |||
JP2004527486A | 2004-09-09 | |||
JPS5268177A | 1977-06-06 | |||
JP2005515176A | 2005-05-26 | |||
JP2004517059A | 2004-06-10 | |||
JP2002544196A | 2002-12-24 | |||
JP2007502786A | 2007-02-15 | |||
JP2004527486A | 2004-09-09 | |||
JPS5268177A | 1977-06-06 |
Foreign References:
WO2005007083A2 | 2005-01-27 | |||
US20050059678A1 | 2005-03-17 | |||
WO2002083622A2 | 2002-10-24 | |||
WO2005007083A2 | 2005-01-27 | |||
US20050059678A1 | 2005-03-17 | |||
WO2002083622A2 | 2002-10-24 |
Attorney, Agent or Firm:
Kuro Fukami
Toshio Morita
Yoshihei Nakamura
Yutaka Horii
Hisato Noda
Masayuki Sakai
Nobuo Arakawa
Toshio Morita
Yoshihei Nakamura
Yutaka Horii
Hisato Noda
Masayuki Sakai
Nobuo Arakawa