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Title:
METHOD FOR SUPPRESSING ABDOMINAL PAIN BY REGULATING T-TYPE CALCIUM CHANNEL
Document Type and Number:
Japanese Patent JP2007191483
Kind Code:
A
Abstract:

To provide a method for suppressing abdominal pain by regulating a T-type calcium channel, an abdominal pain inhibitor containing a T-type calcium channel inhibitor as an active ingredient, and a method for screening an abdominal pain inhibitor by investigating a T-type calcium channel inhibitor activity.

There are provided the method for suppressing abdominal pain comprising activating a function of alpha 1G T-type calcium channel to suppress abdominal pain in a central nervous system and suppressing functions of alpha 1H and alpha 1I T-type calcium channels to suppress abdominal pain in a peripheral nervous system, the abdominal pain inhibitor containing a T-type calcium channel inhibitor as an active ingredient, and the method for screening an abdominal pain inhibitor by investigating a T-type calcium channel inhibitor activity. In the method for suppressing abdominal pain by regulating a T-type calcium channel, abdominal pain can be suppressed by a precise mechanism and regulated without side effect.

COPYRIGHT: (C)2007,JPO&INPIT


Inventors:
SHIN HEE-SUP
KIM DAE-SOO
KIM CHAN-KI
Application Number:
JP2007054025A
Publication Date:
August 02, 2007
Filing Date:
March 05, 2007
Export Citation:
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Assignee:
KOREA ADVANCED INST SCI & TECH
International Classes:
A61K45/00; G01N33/50; A61K31/00; A61K31/4184; A61K33/00; A61K33/24; A61P1/00; A61P25/00; A61P25/02; A61P25/04; A61P29/00; A61P43/00; G01N33/15; G01N33/68
Foreign References:
WO1999028342A21999-06-10
WO1995004028A11995-02-09
Attorney, Agent or Firm:
清水 初志