Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHOD FOR TOTALLY SYNTHESIZING ECTEINASCIDIN, INTERMEDIATE USED FOR THE TOTAL SYNTHESIS AND HAVING STRUCTURE ANALOGOUS TO THE ECTEINASCIDIN, AND METHOD FOR SYNTHESIZING THE INTERMEDIATE
Document Type and Number:
Japanese Patent JP2003221395
Kind Code:
A
Abstract:

To obtain an intermediate capable of efficiently synthesizing an ecteinascidin, and a compound which facilitates the search for an analogue of ecteinascidin.

The intermediate for the total synthesis of the ecteinascidin is the one having the ecteinascidin skeleton five-membered ring structure and represented by formula 2 (wherein there is an OH group in position 4, a substituent R5 on the N atom in position 12 is trichloroethoxycarbonyl (Troc), and these groups are susceptible to the introduction of various groups thereinto under mild conditions).


Inventors:
FUKUYAMA TORU
SUGA TOSHIYUKI
Application Number:
JP2002019360A
Publication Date:
August 05, 2003
Filing Date:
January 29, 2002
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
JAPAN SCIENCE & TECH CORP
International Classes:
C07B61/00; C07C269/06; C07C271/22; C07D317/64; C07D405/06; C07D413/04; C07D451/14; C07D471/08; C07D491/22; C07D493/22; C07D498/18; C07D513/22; C07D515/22; C07F7/18; (IPC1-7): C07D515/22; C07C269/06; C07C271/22; C07D317/64; C07D451/14; C07D491/22
Attorney, Agent or Firm:
Miyamoto Harumi