Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
METHODS FOR TREATING TYPE 2 DIABETES IN PATIENTS RESISTANT TO PREVIOUS TREATMENT WITH OTHER ANTI-DIABETIC DRUGS, EMPLOYING SGLT2 INHIBITOR AND COMPOSITIONS THEREOF
Document Type and Number:
Japanese Patent JP2017160212
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide methods for treating a type 2 diabetes in a patient for whom therapeutic regimens with one or more oral and/or injectable anti-diabetic agents have failed.SOLUTION: A method for treating a type 2 diabetes in a mammalian patient who has previously been treated with one or more oral anti-diabetic agents and/or one or more injectable anti-diabetic agents (e.g., insulin), which treatment has failed, comprises administering to the patient in need of treatment a therapeutically effective amount of an SGLT2 inhibitor. The SGLT2 inhibitor is a compound represented by dapagliflozin or dapagliflozin-PGS and is administered at a dose from about 0.5 to about 200 mg/day, and insulin or other oral anti-diabetic agents are also administered at a dose as prescribed by a physician or as described in the PDR.SELECTED DRAWING: None

Inventors:
PAUL STRUMPH
STEPHANIE MORAN
JAMES LIST
Application Number:
JP2017074526A
Publication Date:
September 14, 2017
Filing Date:
April 04, 2017
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
ASTRAZENECA AB
ASTRAZENECA UK LTD
International Classes:
A61K45/00; A61K31/155; A61K31/195; A61K31/351; A61K31/40; A61K31/403; A61K31/4365; A61K31/4409; A61K31/4439; A61K31/517; A61K31/616; A61K31/64; A61K38/22; A61K38/28; A61K45/06; A61P3/10; A61P5/50; A61P43/00
Foreign References:
US20080234366A12008-09-25
Other References:
ABDUL-GHANI M A: "INHIBITION OF RENAL GLUCOSE REABSORPTION: A NOVEL STRATEGY FOR ACHIEVING GLUCOSE 以下備考", ENDOCRINE PRACTICE, vol. V14 N6, JPN6014028225, September 2008 (2008-09-01), US, pages 82 - 790
メルクマニュアル 第18版 日本語版, JPN6016048733, 2007, JP, pages 1352 - 1360
浜口朋也 他, 日本臨床66巻 増刊号7(通巻第943号) 新時代の糖尿病学(3)−病因・診断・治療研究の進歩−, JPN6016048734, 2008, JP, pages 356 - 361
Attorney, Agent or Firm:
Samejima Mutsumi
Nagatoshi Shinagawa
Mizuhara Masahiro