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Title:
MUCOSAL BOOSTING FOLLOWING PARENTERAL PRIMING
Document Type and Number:
Japanese Patent JP2013053162
Kind Code:
A
Abstract:

To provide compositions and methods for enhancing mucosal and systemic immunity to various antigens, including the pathogens or cancers, having or not having effective vaccines and/or treatments at present.

The method for bringing an immune response in a subject includes steps of: (a) parenterally administering a first immunogenic composition comprising one or more polypeptide antigens and; and (b) mucosally administering a second immunogenic composition comprising one or more antigens, thereby inducing an immune response in the subject.


Inventors:
O'HAGAN DEREK
Application Number:
JP2012000274421
Publication Date:
March 21, 2013
Filing Date:
December 17, 2012
Export Citation:
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Assignee:
NOVARTIS VACCINES & DIAGNOSTIC
International Classes:
A61K39/00; C12N15/09; A61K9/48; A61K38/00; A61K39/02; A61K39/09; A61K39/095; A61K39/102; A61K39/116; A61K39/12; A61K39/145; A61K39/155; A61K39/21; A61K39/245; A61K39/29; A61K39/295; A61K39/385; A61K47/26; A61K47/34; A61K47/42; A61K47/48; A61K48/00; A61P31/04; A61P31/12; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P35/00; C12N15/31; C12N15/48; A61K9/00; A61K9/16
Attorney, Agent or Firm:
Shusaku Yamamoto
Morishita Natsuki