N-ACETYLLACTOSAMINYL-CELLOOLIGOSACCHARIDE DERIVATIVE AND METHOD FOR PRODUCING THE SAME

Japanese Patent JP2003212890

A

To provide a non-natural type new cellooligosaccharide derivative, and to provide a method for producing the same.

This method for producing the new cellooligosaccharide derivative, an N-acetyllactosaminyl-cellooligosaccharide derivative, comprises the following process: using a cellooligosaccharide or a derivative thereof as a saccharide receptor and an oxazoline derivative of N-acetyllactosamine as a saccharide donor, a chitinase is subjected to them under alkaline conditions to obtain the objective N-acetyllactosaminyl-cellooligosaccharide derivative where N-acetyllactosamine is transferred via a β-1,4-linkage to the non-reduced terminal of the cellooligosaccharide or the derivative thereof; wherein it is preferable that the chitinase (preferably, Bacillus-derived one) be subjected to both the saccharide receptor and donor under the condition of pH 8-10.

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SHODA SHINICHIRO
MISAWA YOSHITOMO
KURIYAMA MASAHISA
FUJITA MASAYA
WATANABE TSUYOSHI

JP2002011601A

July 30, 2003

January 21, 2002

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YAIZU SUISANKAGAKU IND CO LTD

C12P19/26; C07H13/02; C07H15/04; C07H15/14; C08B37/00; (IPC1-7): C07H13/02; C07H15/04; C07H15/14; C08B37/00; C12P19/26

Shigeru Matsui

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