【発明の名称】N-フエニルスルホニル-N′-ピリミジニル尿素および同トリアジニル尿素

Japanese Patent JPH0688980

B2

N-Phenylsulfonyl-N'-pyrimidinyl- and -triazinylureas of the formula I (I) wherein A is 3,3,3-trifluoropropyl or 3,3-difluorobutyl, R1 is hydrogen, halogen, nitro, cyano, C1-C4-alkyl, C1-C4-haloalkyl, C1-C4-alkoxy, C1-C4-alkylthio, C1-C4-alkylsulfinyl, C1-C4-alkylsulfonyl, -CO-R6, -NR7R8, -CO-NR9R10 or -SO2-NR11R12, R2 is hydrogen, halogen, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkylthio, C1-C4-alkylsulfinyl or C1-C4-alkylsulfonyl, R3 and R4 independently of one another are each hydrogen, halogen, C1-C4-alkyl, C1-C4-haloalkyl, C2-C4-haloalkoxy, C1-C4-alkylthio, C1-C4-haloalkylthio, C2-C4-alkoxyalkyl, C1-C4-alkoxy or -NR12R13, R5 is hydrogen, C1-C4-alkyl or C1-C4-alkoxy, R6 is C1-C4-alkoxy, C1-C4-haloalkoxy, C1-C4-alkylthio, C2-C6-alkoxyalkoxy, hydrogen, C1-C4-alkyl or C1-C4-haloalkyl, R7, R8, R9, R10, R11, R12 and R13 independently of one another are each hydrogen or C1-C4-alkyl, E is nitrogen or the methine bridge, and Z is oxygen or sulfur; and also the salts of these compounds.

WO/2020/106780	BIS-OCTAHYDROPHENANTHRENE CARBOXAMIDE DERIVATIVES AND PROTEIN CONJUGATES THEREOF FOR USE AS LXR AGONISTS
WO/2020/102506	ARYL HYDROCARBON RECEPTOR (AHR) ACTIVATOR COMPOUNDS AS CANCER THERAPEUTICS
JP2012092103	ESTROGEN RECEPTOR MODULATOR

Villy-Miya-
Conrad Ertre

JP5749584A

November 09, 1994

March 27, 1984

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Ciba-Geigy-Actien Gezelshyaft

C07D249/16; A01N43/70; A01N47/36; C07C67/00; C07C301/00; C07C309/86; C07C311/15; C07C311/16; C07C311/17; C07C311/29; C07C311/39; C07C311/53; C07C311/65; C07C325/00; C07C331/16; C07C331/32; C07D239/42; C07D239/46; C07D239/47; C07D239/48; C07D239/52; C07D239/56; C07D239/69; C07D251/16; C07D251/18; C07D251/22; C07D251/46; C07D251/52; C07D521/00; C07C; (IPC1-7): C07D239/42; A01N47/36; C07D239/47; C07D239/48; C07D239/52; C07D239/56; C07D251/16; C07D251/46

JPS57112378A

US4127405A
US4169719A

Wakabayashi Tadashi

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