NEW AMINOGLYCOSIDE DERIVATIVES AND PROCESS FOR MANUFACTURE THEREOF

Title:

NEW AMINOGLYCOSIDE DERIVATIVES AND PROCESS FOR MANUFACTURE THEREOF

Document Type and Number:

Japanese Patent JPS5259134

Kind Code:

A

Abstract:

1,2'-di-N-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and 1,6'-di-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and their acid addition salts are valuable as antibacterial agents. Also disclosed are 2'-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitol antibacterial agents which are also useful as intermediates in the preparation of the 1,2'-di-N-alkyl-4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols. Preferred compounds of this invention include 1,2'-di-N-ethylsisomicin and 1,6'-di-N-ethylsisomicin.

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Inventors:

JIYON JIEI RAITO
PIITAA JIEI ERU DANIERUSU
ARAN KEI MARAAMUSU
TATSUTANAHARI ERU NAGABUTSUSHI

Application Number:

JP13227076A

Publication Date:

May 16, 1977

Filing Date:

November 02, 1976

Export Citation:

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Assignee:

SCHERICO LTD

International Classes:

A61K31/70; A61K31/7028; A61K31/7034; A61K31/7036; A61P31/04; C07H15/234; C07H15/236; (IPC1-7): A61K31/71; C07H1/00; C07H15/22

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