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Title:
NEW APOPTOSIS-INDUCING AGENT
Document Type and Number:
Japanese Patent JP2003171278
Kind Code:
A
Abstract:

To provide a new and easy to synthesize apoptosis-inducing agent exhibiting the apoptosis-inducing activity against various cancer cell lines in a lower concentration and also exhibiting cytotoxicity in the lower concentration.

This apoptosis-inducing agent has a 2 ring core structure expressed by the following general formula (1) as a base skeleton, and consists of e.g. a synthetic intermediate, etc., of halichlorine which is a kind of a natural product having a cell adhesion-controlling activity.


Inventors:
ITO KOJI
SHISHIDO KOZO
SHINDO MITSURU
Application Number:
JP2001000372050
Publication Date:
June 17, 2003
Filing Date:
December 05, 2001
Export Citation:
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Assignee:
JAPAN SCIENCE & TECH CORP
International Classes:
C07D455/00; A61K31/438; A61K31/695; A61P29/00; A61P31/12; A61P35/00; A61P37/02; A61P43/00; C07D498/04; C07F7/18; (IPC1-7): A61K31/438; A61K31/695; A61P29/00; A61P31/12; A61P35/00; A61P37/02; A61P43/00; C07F7/18
Attorney, Agent or Firm:
佐伯 憲生