Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
NEW CYCLOPROPANE DERIVATIVE
Document Type and Number:
Japanese Patent JPH04283571
Kind Code:
A
Abstract:

PURPOSE: To obtain a new compound expectable as an antiviral agent, etc.

CONSTITUTION: A compound expressed by formula I (B is nucleic acid base derivative; R1 and R2 are H or protecting group of OH), e.g. 1-1-1,9-[2,2- bishydroxymethyl-1-cyclopropyl]adenine. The above-mentioned compound is obtained by reacting a compound expressed by formula II with a compound expressed by formula III, providing a compound expressed by formula IV, then subjecting the resultant compound expressed by formula IV to cyclizing reaction, further reducing the prepared compound, etc. A purine base expressed by formula V (X1 is H, amino, OH or halogen; X2 is H or amino) and a pyrimidine base expressed by formula VI (Y1 is amino or OH; Y2 is H, halogen, alkyl, etc.) are cited as the B.


Inventors:
KATO KUNIMOTO
TAKITA TOMOHISA
Application Number:
JP7044391A
Publication Date:
October 08, 1992
Filing Date:
March 12, 1991
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
NIPPON KAYAKU KK
International Classes:
A61K31/505; A61K31/52; A61K31/522; A61P31/12; A61P35/00; C07D239/47; C07D239/54; C07D239/553; C07D473/00; C07D473/16; C07D473/18; C07D473/30; C07D473/32; C07D473/34; C07D473/40; (IPC1-7): A61K31/505; A61K31/52; C07D239/47; C07D239/54; C07D239/553; C07D473/00; C07D473/16; C07D473/18; C07D473/30; C07D473/32; C07D473/34; C07D473/40