Title:
NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS
Document Type and Number:
Japanese Patent JP2006342182
Kind Code:
A
Abstract:
To provide a intermediate for producing oxabispidine compounds useful as antiarrhythmics and its production method.
There is provided epoxy compounds shown by general formula (XLII), wherein R1a expresses an aryl sulfonyl group or the like, and R41-R46 independently express H or 1-3C alkyl. The compounds (XLII) are produced by making R1aNH2 a starting material and react with a specific compound having a leaving group at the α position of a epoxy group.
Inventors:
BJOERE ANNIKA
BJOERSNE MAGNUS
CLADINGBOEL DAVID
HOFFMAN KURT-JUERGEN
PAVEY JOHN
PONTEN FRITIOF
STRANDLUND GERT
SVENSSON PEDER
THOMSON COLIN
WILSTERMAN MICHAEL
BJOERSNE MAGNUS
CLADINGBOEL DAVID
HOFFMAN KURT-JUERGEN
PAVEY JOHN
PONTEN FRITIOF
STRANDLUND GERT
SVENSSON PEDER
THOMSON COLIN
WILSTERMAN MICHAEL
Application Number:
JP2006226089A
Publication Date:
December 21, 2006
Filing Date:
August 23, 2006
Export Citation:
Assignee:
ASTRAZENECA AB
International Classes:
C07D303/36; A61K31/535; A61K31/537; A61K31/538; A61K31/5386; A61P9/06; C07B61/00; C07D265/30; C07D295/16; C07D295/26; C07D303/48; C07D498/00; C07D498/08; C07D513/00; C07D515/02; C07D519/00; A61K; A61P; C07D
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
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