Title:
新規なプロセスおよび中間体
Document Type and Number:
Japanese Patent JP7001597
Kind Code:
B2
Abstract:
The present invention relates to a new chemical synthesis, intermediates and catalysts useful for the preparation of the neprilysin (NEP) inhibitor sacubitril. It further relates to new intermediate compounds and their use for said new chemical synthesis route.
Inventors:
Kleinbeck-Linikar, Florian Karl
Martin, Benjamin
Pen, gerhard
Venturoni, Francesco
Shrama, Thierry
Latch, Thomas
Thomas Almendinger
Wittfeld, Bernhard
Filipponi, Paolo
Martin, Benjamin
Pen, gerhard
Venturoni, Francesco
Shrama, Thierry
Latch, Thomas
Thomas Almendinger
Wittfeld, Bernhard
Filipponi, Paolo
Application Number:
JP2018530031A
Publication Date:
January 19, 2022
Filing Date:
December 08, 2016
Export Citation:
Assignee:
Novartis Age
International Classes:
C07C69/738; C07C51/08; C07C57/46; C07C67/08; C07C227/08; C07C227/22; C07C229/34; C07C239/18; C07C313/06; C07D207/38; C07D265/02
Domestic Patent References:
| JP2010515698A | ||||
| JP2013537555A |
Foreign References:
| EP0511021A1 |
Other References:
Soliman, Gabra; Youssef, Abdel Hamid Ahmed,Syntheses in naphthalene series. V. Action of sulfuric acid on substituted ethyl γ-phenylacetoacetates,Journal of the Chemical Society,1954年,4655-9
Attorney, Agent or Firm:
Hiroshi Kobayashi
Eiji Katayama
Norio Omori
Mitsuru Hakoda
Eiji Katayama
Norio Omori
Mitsuru Hakoda