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Title:
結核の診断のための核酸標的としてのRD9およびIS6110の使用、ならびにマルチプレックス-コンプライアントIS6110およびRD9標的の提供
Document Type and Number:
Japanese Patent JP5254016
Kind Code:
B2
Abstract:
The present invention relates to the use of both RD9 and IS6110 as nucleic acid targets, for the specific and sensitive detection of a mycobacterium of the Mycobacterium tuberculosis complex (MtbC), and/or for the specific and sensitive discrimination of Mycobacterium tuberculosis and Mycobacterium canetti on one hand, from the other strains of said MtbC on the other hand. Advantageously, said MtbC detection and said species discrimination can be made in a single amplification run (multiplex PCR). The means of the invention are advantageous tools for the diagnosis of tuberculosis.

Inventors:
Clarébou, Gerve
Savoy, chantal
Application Number:
JP2008529475A
Publication Date:
August 07, 2013
Filing Date:
September 05, 2005
Export Citation:
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Assignee:
Bio-Rad Innovations
International Classes:
C12N15/09; C12Q1/04; C12Q1/68
Domestic Patent References:
JP2005518203A
Foreign References:
WO2005064016A1
Other References:
J. Clin. Pathol.,2004年,Vol. 57, No. 11,pp.1185-1192
J. Clin. Microbiol.,2002年,Vol. 40, No. 7,pp.2339-2345
Attorney, Agent or Firm:
Kurata Masatoshi
Yoshihiro Fukuhara
Makoto Nakamura
Nobuhisa Nogawa
Toshio Shirane
Takashi Mine
Kocho Chojiro
Naoki Kono
Katsu Sunagawa
Morisezo Iseki
Tatsushi Sato
Takashi Okada
Mihoko Horiuchi
Takenori Masanori