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Title:
S1P5受容体の作動薬および拮抗薬ならびにそれらの使用方法
Document Type and Number:
Japanese Patent JP2012517446
Kind Code:
A
Abstract:
Disclosed are compounds that are agonists or antagonists of the S1P5 receptor, compositions comprising said compounds, and methods of using said compounds and compositions. In certain embodiments, said compounds are 1-benzylazetidine-3-carboxylic acid derivatives. In certain embodiments, said methods relate to the treatment of neuropatic pain and/or a neurodegenerative disorder. In certain embodiments, said compounds may be used in combination with a second therapeutic agent.

Inventors:
Harris, Christopher M
Hobson, Adrian Day
Wilson, Noel S
Application Number:
JP2011549346A
Publication Date:
August 02, 2012
Filing Date:
February 10, 2010
Export Citation:
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Assignee:
ABBOTT LABORATORIES
International Classes:
C07C69/757; A61K31/137; A61K31/196; A61K31/341; A61K31/397; A61K31/40; A61K31/4015; A61K31/403; A61K31/4045; A61K31/422; A61K31/427; A61K31/4427; A61K31/445; A61K31/695; A61K45/00; A61P5/14; A61P9/00; A61P13/12; A61P25/00; A61P25/02; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P43/00; C07C217/56; C07C229/14; C07C229/48; C07C229/50; C07D205/04; C07D207/08; C07D207/16; C07D207/27; C07D209/02; C07D211/60; C07D211/62; C07D307/22; C07D401/06; C07D401/10; C07D403/06; C07D405/06; C07D405/10; C07D409/06; C07D409/10; C07D409/12; C07D413/06; C07D417/10; C07F7/10
Attorney, Agent or Firm:
Kawaguchi International Patent Office