OPTICALLY ACTIVE FR-900482, ITS ANALOGUE COMPOUND AND SYNTHETIC INTERMEDIATE COMPOUND, AND METHOD FOR PRODUCING THE SAME

Title:

OPTICALLY ACTIVE FR-900482, ITS ANALOGUE COMPOUND AND SYNTHETIC INTERMEDIATE COMPOUND, AND METHOD FOR PRODUCING THE SAME

Document Type and Number:

Japanese Patent JP3710708

Kind Code:

B2

Abstract:

PROBLEM TO BE SOLVED: To obtain FR900482 expectable of new development of a new antitumor antibiotic and its application and its analogue and to provide a method for synthesizing a synthetic intermediate.
SOLUTION: The FR900482 and its analogue or its enantiomer or diastereomer is synthesized by starting from a coupling reaction of a triflate compound with an optically active acetylene compound.

Inventors:

Tohru Fukuyama
Hidetoshi Tokuyama

Application Number:

JP2000404281A

Publication Date:

October 26, 2005

Filing Date:

December 14, 2000

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Assignee:

Japan Science and Technology Agency

International Classes:

C07D317/20; A61K31/537; A61P35/00; C07B41/04; C07B43/04; C07B53/00; C07B61/00; C07D491/056; C07D498/08; C07D498/18; (IPC1-7): C07D498/18; C07D317/20; C07D491/056; C07D498/08

Domestic Patent References:

JP2001247573A

Other References:

J.Am.Chem.Soc.,114, pp383-385 (1992)

Attorney, Agent or Firm:

Toshio Nishizawa

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