Title:
【発明の名称】敗血症治療において治療に用いる対象としての外膜タンパク質A、ペプチドグリカン関連リポタンパク質およびムレインリポタンパク質
Document Type and Number:
Japanese Patent JP2003507433
Kind Code:
A
Abstract:
The present invention relates to three outer membrane proteins conserved among Gram-negative bacteria, OmpA, PAL, and MLP. The invention provides vaccines and polypeptides useful for passive and active immunization against Gram-negative bacteria, as well as methods of preventing and treating Gram-negative sepsis.
Inventors:
Warren, H. Schau
Hermann, Judith
Kernick, James T.
Hermann, Judith
Kernick, James T.
Application Number:
JP2001518084A
Publication Date:
February 25, 2003
Filing Date:
August 18, 2000
Export Citation:
Assignee:
The General Hospital Corporation
International Classes:
C12N5/10; A61K39/00; A61K39/39; A61K39/395; A61P31/04; C07K16/12; (IPC1-7): A61K39/00; A61K39/39; A61K39/395; A61P31/04; C12N5/10
Attorney, Agent or Firm:
Kiyokazu