Title:
PHARMACEUTICAL COMPOSITION CONTAINING POLYPEPTIDE DERIVED FROM BOTULINUM TOXIN AS ACTIVE COMPONENT AND HAVING ANALGESIC ACTION
Document Type and Number:
Japanese Patent JP2009132672
Kind Code:
A
Abstract:
To provide uses of polypeptides derived from botulinum toxin and a pharmaceutical composition having more effective analgesic action.
Provided are a pharmaceutical composition containing polypeptide components free from non-toxin and nontoxic hemagglutinin (HA) among polypeptides derived from botulinum toxin as active components, more particularly, pharmaceutical composition containing polypeptides as active components, wherein the polypeptide components free from non-toxin and nontoxic HA have a molecular weight of about 150 kDa.
Inventors:
KUBOKI TAKUO
MATSUKA YOSHIZO
OGUMA KEIJI
KITAMURA YOICHI
MATSUKA YOSHIZO
OGUMA KEIJI
KITAMURA YOICHI
Application Number:
JP2008182218A
Publication Date:
June 18, 2009
Filing Date:
July 14, 2008
Export Citation:
Assignee:
UNIV OKAYAMA
International Classes:
A61K38/00; A61P25/04; A61P29/02
Domestic Patent References:
| JP2003531127A | 2003-10-21 |
Other References:
JPN7013002424; 小熊 惠二 等: 'ボツリヌス神経毒素製剤の臨床応用' 医学のあゆみ Ｖｏｌ．２１６， Ｎｏ．３, 2006, ｐ．２５１-２５２
JPN7012002645; 横山光彦、他: '改良型ボツリヌス毒素を用いたトランスレーショナルリサーチ' 西日本泌尿器科 第６８巻、第６号, 20060620, ｐ．２３４-２３８
JPN7012002645; 横山光彦、他: '改良型ボツリヌス毒素を用いたトランスレーショナルリサーチ' 西日本泌尿器科 第６８巻、第６号, 20060620, ｐ．２３４-２３８
Attorney, Agent or Firm:
Takashi Shoji
Yuriko Shinobu
Takuya Osugi
Aki Soga
Yuriko Shinobu
Takuya Osugi
Aki Soga