Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PHARMACEUTICAL COMPOSITION FOR SUSTAINED RELEASE OF TRIMETAZIDINE
Document Type and Number:
Japanese Patent JP2013159609
Kind Code:
A
Abstract:

To provide a composition, wherein an inner phase includes trimetazidine and an outer layer includes a retarder and an anti-aggregation agent, for sustained release of trimetazidine.

In a composition: a retarder is selected from among ethylcellulose, cellulose acetate, cellulose acetate butyrate, cellulose acetate propionate, cellulose acetate phthalate, hydroxypropyl methylcellulose acetate succinate and/or polymethacrylate; and an anti-aggregation agent is selected from among talc, colloidal silicon dioxide, magnesium stearate, stearic acid and/or sodium fumaryl stearate.


Inventors:
GENTY PATRICK
HERMELIN CHRISTOPHE
PEAN JEAN-MANUEL
Application Number:
JP2013000018173
Publication Date:
August 19, 2013
Filing Date:
February 01, 2013
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
SERVIER LAB
International Classes:
A61K31/495; A61K9/48; A61K9/50; A61K47/02; A61K47/10; A61K47/12; A61K47/14; A61K47/32; A61K47/34; A61K47/38; A61P9/00; A61P27/02
Domestic Patent References:
JPH07258086A1995-10-09
Foreign References:
WO2010086868A12010-08-05
US20110274751A12011-11-10
WO2009060952A12009-05-14
WO2003043610A22003-05-30
Other References:
改訂 医薬品添加物ハンドブック, vol. 第5版, JPN6016041736, 2007, pages 256 - 544
医薬品添加物事典 2007, vol. 第1版, JPN6016041738, 2007, pages 2 - 6
Attorney, Agent or Firm:
Patent business corporation Tsukuni
Hajime Tsukuni
Yasuo Yanagibashi
Satoko Ito
Keiko Ozawa
Toshio Miyake
Yasuhiro Oguni
Yoko Tanaka
Yoshinori Ikukawa
Akio Shibata