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Patent Searching and Data


Title:
PHOSPHINATE ESTER
Document Type and Number:
Japanese Patent JPH07304783
Kind Code:
A
Abstract:

PURPOSE: To obtain a novel phosphinate ester that is useful as a starting material for producing an antiviral agent and can eliminate the protecting group under mild basic conditions by reacting phosphinic acid with an alcohol or a chloroformic ester.

CONSTITUTION: This novel phosphinate ester is represented by formula I (R1 is a 1-10C aliphatic group; R2 is a 1-10C aliphatic group, a 6-10C aromatic group; R3 is a 1-8C aliphatic group, a 3-8C alicyclic group, a 6-15C aromatic group and the like where in the case that R1 and R2 are each methyl, R3 is not ethyl; in the case that R1 is methyl and the R3 is ethyl, R2 is not p-aminophenyl), and produces a product that can eliminate the protecting group under mild basic conditions and is useful as a starting substance for producing antiviral action. This compound is prepared by esterification of phosphinic acid represented by formula II with an alcohol of the formula: R3OH or with a chloroformic ester represented by the formula: ClCOOR3.


Inventors:
ERITSUKU KIISU BEIRISU
Application Number:
JP5829694A
Publication Date:
November 21, 1995
Filing Date:
March 04, 1994
Export Citation:
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Assignee:
CIBA GEIGY AG
International Classes:
C07F9/32; C07F9/48; C07H7/02; C07H9/04; C07H19/10; (IPC1-7): C07F9/32
Attorney, Agent or Firm:
Hajime Tsukuni (1 person outside)