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Title:
【発明の名称】カッパアゴニストとしてのピロリジニルおよびピロリニルエチルアミン化合物
Document Type and Number:
Japanese Patent JP3195368
Kind Code:
B2
Abstract:
A compound of the following formula:and the salts thereof wherein A is hydrogen, halo, or hydroxy, broken line represents an optional double bond with proviso that if the broken line is a double bond, then A is absent; Ar1 is optionally substituted phenyl; Ar2 is aryl or heteroaryl selected from phenyl, napththyl, or pyridyl, the aryl or heteroaryl being optionally substituted; R1 is hydrogen, hydroxy, or C1-C4 alkyl; and R2 and R3 are independently selected from optionally substituted C1-C7 alkyl, C3-C6 cycloalkyl, C2-C6 alkenyl, C2-C6 alkynyl, or R2 and R3, together with the nitrogen atom to which they are attached, form an optionally substituted pyrrolidine. These compounds are useful as kappa agonists.

Inventors:
Fumitaka Ito
Yoji Kondo
Application Number:
JP51443398A
Publication Date:
August 06, 2001
Filing Date:
August 21, 1997
Export Citation:
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Assignee:
Pfizer Pharmaceuticals Co., Ltd.
International Classes:
A61K31/40; A61K31/4015; A61K31/4025; A61K31/4035; A61K31/4427; A61K31/443; A61K31/4433; A61K31/4439; A61K31/5377; A61P1/06; A61P19/02; A61P23/00; A61P25/00; A61P25/28; A61P29/00; A61P43/00; C07C237/30; C07C239/18; A61P25/04; C07D207/10; C07D207/12; C07D207/20; C07D207/24; C07D213/81; C07D213/82; C07D333/40; C07D401/12; C07D403/12; C07D405/12; C07D409/12; C07F7/18; C07D; (IPC1-7): C07D207/12
Attorney, Agent or Firm:
Hiroshi Kobayashi