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Title:
PREPARATION OF 4-(S)-5-METHOXYCARBONYL-1-(S)-HY DROXYPENTYL-5-(R)-HYDROXYMETHYL-IMIDAZOLIDINONE AND ITS DERIVATIVE
Document Type and Number:
Japanese Patent JPS54109972
Kind Code:
A
Abstract:

NEW MATERIAL:4-(S)-[5-Methoxycarbonyl-1-(S)-hydroxypentyl]-5-(R)-hydroxymethyl-imidazolidinone of formula I (when R1 is CH2C6H5, R2 is the group of formula II, or when R1 is OH, R2 is the group of formula III.

EXAMPLE: Benzyl 2,3-diamino-2,3-N,N'-carbonyl-2,3,5,6-tetradeoxy-5,6-didehydro- 6-C-methoxycarbonylethylene-β-D-ribohexofuranoisde.

USE: Starting materials for synthesizing a variety of organic compounds, especially a kind of vitamin, natural type (+)-biotin.

PREPARATION: A saturated hemiacetal of formula IV is treated with a reducing agent of metal hydride as sodium borohydride in a solvent as methanol to form the objective compound of formula I. The compound of formula IV is also novel.


Inventors:
EMOTO SAKAE
OORUI HIROSHI
SUEDA NORIYOSHI
Application Number:
JP1978000017063
Publication Date:
August 29, 1979
Filing Date:
February 15, 1978
Export Citation:
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Assignee:
RIKAGAKU KENKYUSHO
International Classes:
C07D233/40; C07D495/04; C07H9/06; C07H15/18; (IPC1-7): C07H15/18



 
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