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Patent Searching and Data


Title:
PRESSURE-MEDIATED TRANSPORTATION OF MOLECULE OR MICROPARTICLE INTO CELL
Document Type and Number:
Japanese Patent JP2008237221
Kind Code:
A
Abstract:

To provide a method for enhancing the uptake by a cell and of an atom, a molecule or a particle of 10 m.

The method involves (a) a step for bringing a cell into contact with a liquid medium containing the atom, molecule or particle, (b) a step for maintaining the cell and liquid medium in an enclosed space, and (c) a step for subjecting the enclosed cell and liquid medium to incubation pressure sufficient to enhance the uptake of the atom, molecule or particle. In this method, the incubation pressure is higher than normal pressure by 50 mmHg but 5 atm.


Inventors:
MANN MICHAEL J
DZAU VICTOR J
GIBBONS GARY H
Application Number:
JP2008121322A
Publication Date:
October 09, 2008
Filing Date:
May 07, 2008
Export Citation:
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Assignee:
UNIV LELAND STANFORD JUNIOR
International Classes:
C12N1/00; C12N15/09; A61K31/70; A61K31/7088; A61K45/00; A61K48/00; A61M5/00; A61M5/145; A61M25/00; A61M37/00; A61P43/00; C12M1/00; C12M1/34; C12M3/00; C12M3/04; C12N5/10; C12N15/11; C12N15/113; C12N15/87; C12N15/89; A61F2/958
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi