Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
PRODUCTION OF GAMMA-CHLOROACETOACETIC ACID ESTER
Document Type and Number:
Japanese Patent JPS6025955
Kind Code:
A
Abstract:

PURPOSE: To obtain the titled compound useful as an intermediate of quinacridone (a red pigment) or a raw material of pharmaceuticals, etc., in high yield, by reacting γ-chloroacetoacetyl chloride with an alcohol while removing the by- produced hydrogen chloride from the reaction system.

CONSTITUTION: γ-Chloroacetoacetyl chloride is made to react with an alcohol (e.g. methanol, ethanol, propanol, butanol, n-hexanol, etc.) in an inert solvent (e.g. dichloroethane) at -20W0°C for 5W60min while removing the by-produced hydrogen chloride from the system, to obtain the objective γ-chloroacetoacetic acid ester. The removal of hydrogen chloride can be carried out e.g. by the addition of a hydrogen chloride absorbent to the system, the evacuation of the system or the introduction of an inert gas (e.g. N2, argon, etc.) into the reaction system.


Inventors:
HAKOZAKI SUSUMU
NUMAMOTO NORIYOSHI
NAKAJIMA KAZUHISA
Application Number:
JP1983000134773
Publication Date:
February 08, 1985
Filing Date:
July 22, 1983
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
NIPPON SYNTHETIC CHEM IND
International Classes:
C07C69/675; C07C67/14; C07C69/72; (IPC1-7): C07C67/14; C07C69/72
Domestic Patent References:
JPS56154438A1981-11-30
JPS473807A
JPS5675454A1981-06-22