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Title:
PRODUCTION OF OPTICALLY ACTIVE INABENFIDE USING CULTURED CELL OF PLANT
Document Type and Number:
Japanese Patent JPH04222592
Kind Code:
A
Abstract:

PURPOSE: To produce optically high-purity active inabenfide in high yield, in a short process and in higher optically resolving properties than those of existing method.

CONSTITUTION: 4'-Chloro-2'-benzoyl-isonicotinic acid anilide is used as a substrate and cultured cells of plant capable of asymmetrically reducing 4'-chloro-2'- benzoyl-isonicotinic acid anilide into optically active 4'-chloro-2'-(α- hydroxybenzyl)isonicotinic acid anilide (inabenfide for short) are brought into contact with a substrate compound, which is converted optically active inabenfide and then optically active inabenfide is collected.


Inventors:
FURUYA TSUTOMU
HIROYA MASAO
ICHIKAWA TADASHI
Application Number:
JP1990000418045
Publication Date:
August 12, 1992
Filing Date:
December 21, 1990
Export Citation:
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Assignee:
CHUGAI PHARMACEUTICAL CO LTD
International Classes:
C12N5/04; C12P17/12; C12R1/91; (IPC1-7): C12N5/04; C12P17/12



 
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